Ok.
This is a 'biggie' but to my knowledge I don't know anyone who has ever suffered the effects of Autolysis enough so that it ruins the beer or is even noticeable for that matter. After talking with my friend Phil, he made a very good point. Autolysis is happening. Like it or not, your Yeast will die. And like it or not, they will impart the flavors resulting from their dead bodies, fatty acids and lipids. What many people don't have a handle on is why they never see the effects of this in their beer. There may be some people out there, but I only recall reading one thread where the poster was describing "Soy Sauce" flavor, which is undoubtedly Autolyzed Yeast.
What sets most people into the 'safe' zone often turns out from common practice. That being racking your beer off the trub before it is too old. Here is where it gets complicated. That time depends on a myriad of factors, which are mainly temperature, recipe, Yeast strain and the particular grain bill and hop additions. The latter two being related to the masking ability of the ingredients. There is no 'hard and fast rule' that will allow one to figure out how long beer can sit on the trub. But, there is a balance between the necessary time to fully ferment a batch and a 'safe' time to pull a batch off the trub. Most of the primary fermentation in Ales is finished under 4 days. There is a safety margin here, which I am sure there are people out there playing around. Again, a 7 or 10 day rule on primary is really a habitual working model for many folks, myself included.
I almost always pull beer off the primary at around 10 days and have never noticed anything to do with Autolysis in terms of it making beer taste bad. In my bottle conditioned Ales, there is always a layer of Yeast sediment and again, no off flavors. I know people that have gotten away with leaving a batch on primary for an extended period of time. I did this once, it was on there for almost 3 weeks, fortunately to no ill effect. This suggests that only large amounts of Yeast at warmer temperatures induce the negative effect.
So what have been your experiences? It would be an interesting endeavor over time to collect data from different time lengths on primary and try to see if we get any trends in the data. I can say from experience that an average of 10 days primary with an Ale has never given me noticeable off flavors from Autolysis. I don't brew many Lagers, but due to the decreased fermentation temperature the safe zone probably extends a little, but it should be kept in mind that many Lagers tend to be more delicate recipes (or naked as I like to call them) that won't hide off flavors.



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